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2015f;38(Suppl

10.1081/CEH-200044267 38

Although no physiological or outcome-based claims can be made, the molecule continues to appear in: Enzymatic pathway discussions Cell-signalling research Methyltransferase-related studies Computational modelling of enzyme interactions Small-molecule inhibitor development Because NNMT has been referenced in scientific settings involving metabolic process mapping and cellular signalling, synthetic analogues such as 5-Amino-1MQ remain relevant within modern biochemical interest

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Post-Bariatric Surgery and Malabsorption Syndromes People who have had bariatric surgery or have malabsorption syndromes cant absorb vitamin B12 well

While this is not a side effect in the traditional sense, it's important to be aware that long-term use of high doses for skin-lightening purposes may have unintended consequences and may not be safe
